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Testosterone replacement therapy for men 35 and above

The testicles are the primary source of testosterone. Testosterone therapy may be an option for you as you are at 30 and above. The truth is, many people are misinformed about the treatment’s abilities and limitations. If testosterone therapy sounds like a magic anti-aging potion, you’re not alone.

However, the advantages of testosterone therapy for the decline in testosterone that comes with age are not yet clear. TRT, or Testosterone Replacement Therapy, is becoming increasingly popular as men’s health concerns rise. Testosterone levels naturally decline as we age.

Taking testosterone replacement therapy (TRT) can boost your self-esteem, improve your libido, and possibly even improve your bone density if you’re experiencing a decline in testosterone levels. However, you may wonder when to begin testosterone replacement therapy and whether there are any risks. Discover the things you want to know about Testosterone replacement therapy for healthy aging.

How old should you to begin Testosterone replacement therapy?

Males in their early fifties who are experiencing symptoms of low testosterone may benefit from testosterone replacement therapy (TRT). Starting treatment at this early stage of the decline means that you won’t experience as many adverse side effects as someone in their 60s or 70s.

It is possible that men in their late 30s, for example, will need to begin treatment in their 40s. A full assessment by a doctor is the best way to monitor your testosterone levels.

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Does a naturally decreasing testosterone level cause the aging process?

That is not always the case. There is a slew of symptoms that men can experience as they grow older. Some of the possible side effects of testosterone deficiency include:

  • Sexual dysfunction can occur as a result.

Reduced sexual desire, fewer spontaneous erections (such as while sleeping), and infertility are possible outcomes.

  • Changes in the body.

Changes in your body may include an increase in fat and muscle mass and a decrease in bone density. Gynecomastia, or swollen or tender breasts, is a possibility, as is hair loss on the body. You may be running on less gas than usual.

  • Mood changes.

A lack of motivation and self-confidence have been linked to low testosterone levels. You may experience difficulty concentrating or remembering things, as well as feelings of sadness or depression.

Many other possible causes for these symptoms include medication side effects, obstructive sleep apnoea, thyroid problems, diabetes, and depression. ‘Treatment for these conditions may increase testosterone levels. You can detect a low testosterone level through a blood test.

Is testosterone therapy an effective way to maintain a youthful appearance and sense of well-being?

You can reverse hypogonadism with testosterone therapy, but it’s not clear if it would benefit older men who are otherwise healthy.

Even though some men believe that taking testosterone supplements makes them feel younger and more energetic, there is little evidence to back this up. In the opinion of the American College of Physicians (ACP), there is no evidence that testosterone therapy can increase male vitality or energy (ACP).

Using Testosterone replacement therapy to slow down the effects of aging isn’t without risks.

Among the dangers of testosterone therapy are the following:

Sleep apnea is getting worse, which is when your breathing repeatedly stops and starts while you’re sleeping.

Acne or other skin reactions are examples of this.

Prostatic hyperplasia (benign) and pre-existing cancer are accelerated by stimulating non-cancerous growth in the prostate.

Sperm production is reduced, or the testicles shrink as a result.

Increasing the risk of a blood clot by stimulating the production of too many red blood cells. A clot could break loose, travel through your bloodstream, and land in your lungs, preventing blood from flowing through your body (pulmonary embolism).

According to some studies, the risk of heart disease may be increased by testosterone therapy. More investigation is required.

What is testosterone replacement therapy?

Testosterone levels reach their highest during adolescence and the early years of adulthood, and they begin to fall as you get older. After 30 or 40, this decreases by an average of 1% annually, but individual circumstances may dictate a different percentage.

Among men, the HPG axis is responsible for regulating testosterone production. The anterior pituitary produces LH and FSH due to the hypothalamus producing gonadotropin-releasing hormone (GnRH) (FSH). Afterward, LH stimulates testosterone production by the Leydig cells in the testicles. When testosterone inhibits the release of hypothalamic and anterior pituitary hormones, the process is regulated by a negative feedback loop. About 4% of testosterone is converted to dihydrotestosterone by a reductase enzyme, and 0.2 percent is converted to oestradiol by aromatase. The liver inactivates most testosterone, which is then excreted by the kidneys.

If you’re over the age of 40, you should have your testosterone levels checked to ensure they aren’t dropping because of something else, like a medical condition. The TRT process can begin once this has been established. TRT is available in various forms, including injections, pills, patches, gels, and so on. For those who follow their doctor’s advice, these treatment methods can help restore your testosterone levels and bolster your sense of self-esteem.

Is testosterone therapy something you should discuss with your doctor?

Consider the risks and benefits with your doctor if you’re unsure whether testosterone therapy is right for you. Be prepared for at least two testosterone measurements before you get the go-ahead from your doctor for testosterone therapy.

It’s not a good idea to use testosterone therapy to slow down the effects of natural aging. To raise testosterone levels, your doctor may recommend losing weight and increasing muscle mass through resistance training if you don’t have a medical condition that’s causing your testosterone levels to drop.


The aging process results in lower testosterone levels, but you don’t have to put up with it. You can increase testosterone levels and combat some of the side effects of aging through testosterone replacement therapy (TRT). If you’re looking for a way to improve your mental and physical health, this may be an excellent option for you.

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